######################################################################## Graduate Studies Listserv - ######################################################################## To view this newsletter in a browser, visit: https://listserv.dartmouth.edu/scripts/wa.exe?A2=GRAD;c9dc730e.1710p To ensure that this newsletter is delivered to your inbox, add [log in to unmask] to your address book. ######################################################################## In this Newsletter: * Visit it Biotech Alum, Molly Croteau - still a few spaces * Come Tour Celdara and meet the CEO * Subscription Details ######################################################################## * Visit it Biotech Alum, Molly Croteau - still a few spaces * GRAD Alum Visit - Molly Croteau Date: Friday, October 20, 2017 Time: 12:00pm - 1:30pm Location: Campus: Graduate Studies http://libcal.dartmouth.edu/event/3472101 Come have lunch with GRAD alum, Molly Croteau. 41 Haldemen with lunch provided See bio below: Molly Croteau, Ph.D. in Chemistry Scientist, Bioassays at Avitide, Inc. Lebanon, New Hampshire Molly obtained her Ph.D. in Bioinorganic Chemistry from the Dartmouth Chemistry Department in February of 2016. Her thesis work was developing new methods to understand chemical reduction and oxidation reactions in metalloproteins (proteins that contain metals); specifically a brilliant-blue colored protein called Azurin. In simple terms, she studied how the smallest unit of energy (an electron) changes how the metal interacts or binds with the protein, and how you can detect this electron change in a new way that would help scientists with more complex proteins and metals. While her work would never go on to cure cancer or fight crime, it does lay the foundation to help future researchers develop alternative energy fuels using the simple electron and natural proteins as the workhorse. Molly then applied her fundamental knowledge about binding interactions and obtained a job with Avitide, Inc. right in Lebanon, New Hampshire in February 2016. About Avitide: Avitide has been around since 2013 and was started at one lab bench in Adimab (another Upper Valley biotech company) with roughly 3 employees. We have grown to currently have about 35 employees in Merck’s old space in the Dartmouth Regional Technology Center (DRTC), with a foreseeable expansion in the future. In the biotech world, growing and purifying biological drugs (like insulin) is a long, tedious, and expensive process. Here at Avitide, we design and build unique molecules to help purify biologics for large biopharmaceutical companies, so they can bring the drugs to market directly, or be accepted into clinical trials. We perform these tasks in 3 months, and offer more robust solutions to the current industry. In simple terms, let’s say a company has made a fruit smoothie, but they really only want the banana part of that smoothie from the mixture. Typically, they would pass the smoothie mixture through six to eight different filters, and eventually they would get just the banana part (the pure drug substance). At Avitide, we design and build one filter that separates the banana from the smoothie in one shot, with minimal banana clean up afterwards. Of course, we don’t actually work with smoothies and bananas, but with cell mixtures that contain the expressed drug of choice. Molly is a Bioassay Scientist at Avitide, which entails determining how our molecules interact with the biological drug substances we receive from clients. She uses ForteBio Octet (BLI) technology, along with other binding technologies (ELISA, etc.) to select the best molecules from over 5,000 to 1 or 2 lead candidates. She also is the lead manager for a large and complex multi- year project, which entails data organization and task delegation throughout the entire workforce. Other Info: Molly knew that she wanted to pursue a career in the science industry, opposed to academia, and set her tasks in graduate school to meet this goal. She can offer advice about what techniques most industrial science companies are looking for in an employee, and how you can obtain those techniques during graduate school. She can also answer questions about large companies vs. small companies, postdoc vs. no postdoc, and other general advice. * Come Tour Celdara and meet the CEO * Company Visit - Celdara Date: Tuesday, October 24, 2017 Time: 2:30pm - 4:30pm Location:Lebanon, NH http://libcal.dartmouth.edu/event/3472883 Jake Reeder, PhD, CEO of Celdara Medical (Lebanon, NH) has invited graduate students/postdocs to visit his company. We will meet Jake and other employees at Celdara to get a sense of what they do and how they got their jobs there. We will carpool over to Celdara in Lebanon, NH leaving from the 37 Dewey Field Rd parking lot. We will meet at 2:30 pm. Once everyone has signed-up I will try to figure out carpooling. http://celdaramedical.com/ Celdara Medical gives hope and health to patients by transforming academic innovations into medicines that cure the world’s most challenging diseases. We are a recognized leader with a rich stable of discoveries, developed in concert with premiere research institutions in the US, EU, and beyond. We secure lasting partnerships with inventors and their institutions, and provide the developmental, financial, and business acumen to bridge the gaps between discovery and clinical impact. With robust funding options, operations in greater Boston, Washington DC and New York City, growing affiliates in Seattle and Indianapolis, a wealth of opportunities in our pipeline, and partnerships with industry leaders worldwide, Celdara Medical navigates the path from science to medicine, accelerating innovation to improve human health. ######################################################################## * Subscription Details * You are subscribed to Graduate Studies Listserv. To unsubscribe, visit: https://LISTSERV.DARTMOUTH.EDU/scripts/wa.exe?SUBED1=GRAD&A=1 37 Dewey Field Road, Suite 437 Dartmouth College Hanover, NH 03755 [log in to unmask] http://graduate.dartmouth.edu/ ######################################################################## Dartmouth Graduate Studies ########################################################################